Month: February 2019

Reducing Iron Overload

Reducing Iron Overload – Iron Chelators How is Iron Toxic? In short iron is toxic because it can be a part of a fenton reaction – thereby becoming a free radical. Normal iron levels are generally well managed by the body, but excess iron causes oxidative damage.  Fenton-type’ redox chemistry, reacting with hydrogen peroxide (H2O2) […]


Hemochromatosis What is it? Hemochromatosis is the most common genetic condition in Australia, affecting 1 in 200 people. The gene is the HFE gene. Although some people will have the genes they will have no adverse symptoms, whilst others will have many complications. The reason for this is unknown. Genes involved are HFE C282Y and […]

Acne Vulgaris

Acne Vulgaris Pathogenesis of Acne: – Acne is a Multifactorial Process at Pilosebaceous Unit – the sebaceous gland and hair follicle (1). The main contributing factors are; Genetics Androgens Cortisol Stress Barrier dysfunction Diet Propionibacterium acnes (bacteria commonly found on human skin) IGF/1 – Insulin like growth factor – hormone Acne and inflammation Stimulates the […]